Histone H3 Mouse monoclonal Antibody | MB9021

Histone H3 Mouse monoclonal Antibody | MB9021 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat

Application: WB IHC

Application Range: WB: 1:5000 IHC: 1:100-1:200

Background: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fibre is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures.Covalent modifications of the canonical core histones, including acetylation, phosphorylation, methylation, and monoubiquitination are used to mark nucleosomes to create chromatin domains with a range of functions.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of Histone H3 and does not cross-react with related proteins.

Molecular Weight: ~ 17 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Histone H3.1

Immunogen: This Antibody is produced by immunizing mice with a recombinant protein corresponding to a region of Histone H3.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A affinity purified

Pathway: