Description
HIV-1 p24 Antibody [7F4] | PM-6585 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Virus
Homology: N/A
Immunogen: Mouse monoclonal HIV-1 p24 antibody was raised against a recombinant full-length HIV-1 p24 protein.
Research Area: Infectious Disease, Antibody Pairs
Tested Application: E, WB
Application: PM-6585 can be used for detection of p24 by Western blot or ELISA at 0.2 – 0.5μg/mL.
Specificiy: By Western blot, anti-HIV-1 p24 antibody detects a ~24 kDa, a ~41 kDa, and a ~55 kDa protein, corresponding to HIV-1 p24 and to its precursors p41 and p55, respectively, in HIV-1 samples.
Positive Control 1: Cat. No. 95-153 - Recombinant HIV-1 p24
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 24 kDa, 41 kDa, and 55 kDa
Validation: N/A
Isoform: N/A
Purification: HIV-1 p24 antibody is supplied as protein A purified IgG1.
Clonality: Monoclonal
Clone: 7F4
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: HIV-1 p24 Monoclonal Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration: 1 mg/mL
Storage Condition: HIV-1 p24 Monoclonal Antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Alternate Name: HIV-1 p24 Antibody [7F4] :
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: HIV-1 p24 Monoclonal Antibody: The human immunodeficiency virus type 1 (HIV-1) particle consists of an envelope, a core and the region between the two termed matrix (1) . The HIV-1 Gag protein is a late structural protein that contains four proteins: matrix (p17) , capsid (p24) , nucleocapsid (p7) and the p6 protein (2) . The p24 constitutes the major core component of the virus and shows high degree of sequence conservation among HIV isolates. The Gag p24 has been used as an integral part of multicomponent HIV-1 vaccines (3) .