HKR1 (W154) polyclonal Antibody | BS1923

HKR1 (W154) polyclonal Antibody | BS1923 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Humam

Application: WB IHC

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krueppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. HKR1, also known as Krueppel-related zinc finger protein 1 or zinc finger protein 875, is a 659 amino acid nuclear protein that is thought to play a role in transcriptional regulation. Existing as two alternatively spliced isoforms, HKR1 is a member of the Krueppel C2H2-type zinc-finger protein family and contains thirteen C2H2-type zinc fingers and one KRAB domain. The gene encoding HKR1 maps to human chromosome 19q13.12.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HKR1 (W154) polyclonal Antibody detects endogenous levels of HKR1 protein.

Molecular Weight: ~ 73 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Krueppel-related zinc finger protein 1; Protein HKR1; Zinc finger protein 875; HKR1; ZNF875

Immunogen: Synthetic peptide, corresponding to amino acids 111-160 of Human HKR1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: