HLA-F Polyclonal Antibody | E-AB-65765

HLA-F Polyclonal Antibody | E-AB-65765 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HLA-F, CDA12, HLA-5.4, HLA-CDA12, HLAF

Application: WB

Reactivity: Human, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: N/A

Background: This gene belongs to the HLA class I heavy chain paralogues. It encodes a non-classical heavy chain that forms a heterodimer with a beta-2 microglobulin light chain, with the heavy chain anchored in the membrane. Unlike most other HLA heavy chains, this molecule is localized in the endoplasmic reticulum and Golgi apparatus, with a small amount present at the cell surface in some cell types. It contains a divergent peptide-binding groove, and is thought to bind a restricted subset of peptides for immune presentation. This gene exhibits few polymorphisms. Multiple transcript variants encoding different isoforms have been found for this gene. These variants lack a coding exon found in transcripts from other HLA paralogues due to an altered splice acceptor site, resulting in a shorter cytoplasmic domain.

Concentration: 1 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant fusion protein of human HLA-F (NP_001091949.1).

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 28 kDa/39 kDa/50 kDa

Molecular Weight(Observed): 50 kDa