HMGA2 Polyclonal Antibody | E-AB-53257

HMGA2 Polyclonal Antibody | E-AB-53257 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: HMGA 2, BABL, High mobility group (nonhistone chromosomal) protein isoform I C, High mobility group (nonhistone chromosomal) protein isoform IC, High Mobility Group AT hook 2, High Mobility Group AT hook protein 2, High mobility group AT-hook protein 2, High mobility group protein HMGI C, High mobility group protein HMGI-C, High mobility group protein HMGIC, High mobility group protein I, isoform C, HMGA2, HMGA2, HMGI C, HMGIC, LIPO, Non histone chromosomal architectural protein HMGI C, Non histone chromosomal architectural protein HMGIC, Pygmy, STQTL9

Application: WB, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling, Metabolism, Developmental biology, Neuroscience, Stem cells

Background: This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family. HMG proteins function as architectural factors and are essential components of the enhancesome. This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor. Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation. A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Concentration: 1.02 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human HMGA2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 12 kDa

Molecular Weight(Observed): Refer to figures