HMGB1 polyclonal Antibody | BS7131

HMGB1 polyclonal Antibody | BS7131 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB: 1:500~1:2000 IHC/IF: 1:50~1:200

Background: High mobility group (HMG) proteins 1 and 2 are ubiquitous non-histone components of chromatin. Research suggests that the binding of HMG proteins to DNA induces alterations in the DNA architecture, including DNA bending and unwinding of the helix. HMG proteins synergize with Oct-2, ATF-2, c-Jun and members of the NFκB family to activate transcription.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HMGB1 polyclonal Antibody detects endogenous levels of HMGB1 protein.

Molecular Weight: ~25 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1

Immunogen: Recombinant full length Human HMGB1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: