HMGB4 Antibody| F45888-0.08ML/F45888-0.4ML/R30219

HMGB4 Antibody| F45888-0.08ML/F45888-0.4ML/R30219 | Gentaur UK, US & Europe Distribution

Background: High Mobility Group (HMG) proteins, a group of chromosomal proteins common to all eukaryotes, bind DNA in a non-sequence-specific fashion to promote chromatin function and gene regulation, helping with transcription, replication, recombination, and DNA repair. HMGB4 is HMG2-like, isoform 2, high-mobility group box 4. This gene can be found on Chromosome 1. HMGB4 contains two HMG-box regions, and is found in a variety of eukaryotic chromosomal proteins. HMGB proteins are phosphorylated to various extents. The existence of differentially modified forms increases the number of distinct HMGB protein variants in plant chromatin that may be adapted to certain functions.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human, Rat

Predicted Spacies Reactivity: Bovine

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the HMGB4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This HMGB4 antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 45-73 from the human protein was used as the immunogen for this HMGB4 antibody.

Storage: Aliquot the HMGB4 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A