HNF1A Antibody (Center) [APR32593G]

HNF1A Antibody (Center) [APR32593G] | Gentaur UK, US & Europe Distribution

Product Category: Polyclonal Antibodies

Host: Rabbit

Species Reactivity: H, M

Specificity: This HNF1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 177-205 amino acids from the Central region of human HNF1A.

Cellular Localisation: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00108, ECO:0000269|PubMed:10966642}

Molecular Weight: 67356

Clone: Polyclonal

Gene Name: HNF1A

Gene ID: 6927

Function: Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver (By similarity) . Binds to the inverted palindrome 5'- GTTAATNATTAAC-3' (PubMed:12453420, PubMed:10966642) . Activates the transcription of CYP1A2, CYP2E1 and CYP3A11 (By similarity) .

Summary: Tissue Location: Liver.

Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Application: WB, IF

Dilution: WB--1:1000 IF--1:10~50

Synonyms: Hepatocyte nuclear factor 1-alpha, HNF-1-alpha, HNF-1A, Liver-specific transcription factor LF-B1, LFB1, Transcription factor 1, TCF-1, HNF1A, TCF1