HNRNPR polyclonal Antibody | BS8078

HNRNPR polyclonal Antibody | BS8078 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB IHC IF

Application Range: WB 1:500 - 1:2000 IHC 1:100 - 1:200 IF 1:50 - 1:200

Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing, as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which is the transcript produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus; however, some shuttle between the nucleus and the cytoplasm. Two abundant and ubiquitously expressed members of the hnRNP family are hnRNP D0 and hnRNP R. Specifically, the hnRNP D0 protein contains two RNA-binding domains (RBDs), which bind to both RNA and DNA sequences. hnRNP D0 also possesses a transactivator domain and is involved in transcriptional regulation.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: HNRNPR polyclonal Antibody detects endogenous levels of HNRNPR protein.

Molecular Weight: ~ 71 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Heterogeneous nuclear ribonucleoprotein R; hnRNP R; HNRNPR; HNRPR

Immunogen: Recombinant full length Human HNRNPR.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: