HPS4 Antibody | 16-461

HPS4 Antibody | 16-461 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: A synthetic peptide corresponding to a sequence within amino acids 550-650 of human HPS4 (NP_690054.1) .

Research Area: Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: U-87MG

Positive Control 2: SGC-7901

Positive Control 3: LO2

Positive Control 4: Jurkat

Positive Control 5: Mouse liver

Positive Control 6: N/A

Molecular Weight: Observed: 115kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BLOC3S2, LE, Hermansky-Pudlak syndrome 4 protein, light-ear protein homolog

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC) . BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.