HRAS Antibody | XW-7712

HRAS Antibody | XW-7712 | Gentaur UK, US & Europe Distribution

Host: Chicken

Reactivity: Mouse, Rat

Homology: N/A

Immunogen: 116-189

Research Area: Other

Tested Application: WB

Application: GTPase HRas antibody can be used for the detection of GTPase HRas by Western Blot.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 21.3 kDa (calculated)

Validation: N/A

Isoform: N/A

Purification: Immunoaffinity Purified

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Phosphate-Buffered Saline. No preservatives added.

Concentration: 1 mg/mL

Storage Condition: HRAS antibody can be stored at 4˚C for short term (weeks) . Long term storage should be at -20˚C. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Alternate Name: HRAS1, GTPase HRas, H-Ras-1, CTLO, HAMSV, HRAS1, K-RAS, N-RAS, RASH1, C-H-RAS, H-RASIDX, C-BAS/HAS, C-HA-RAS1, Transforming protein p21, c-H-ras

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: FUNCTION: Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

DISEASE: Defects in HRAS are also the cause of oral squamous cell carcinomas (OSCC) .

PTM: Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.

SIMILARITY: Belongs to the small GTPase superfamily. Ras family.

ENZYME REGULATION: Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP) .