HSP60 (6C8) monoclonal Antibody | MB0177

HSP60 (6C8) monoclonal Antibody | MB0177 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human,Mouse,Rat

Application: WB IF IP

Application Range: WB: 1:1000 IP: 1:50~200 IF: 1:50~200

Background: HSPs (also known as molecular chaperones) fall into six general families: HSP 90, HSP 70, HSP 60, the low molecular weight HSPs, the immunophilins, and the HSP 110 family. The constitutively expressed mitochondrial protein HSP 60 shares the ability to recognize and stabilize proteins during folding, assembly and disassembly with other HSP family members. The mitochondrial and cytosolic localization of HSP 60, combined with its binding and catalysis of folding of newly synthesized proteins destined for the mitochondrial matrix, classify this protein as a molecular chaperone. An additional role of HSP 60 is to act as a cell surface marker forr γ/δ T cell recognition.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: This Antibody detects endogenous levels of HSP60 and does not cross-react with related proteins.

Molecular Weight: Predicted band size:60KDa Observed band size:60KDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: 60 kDa heat shock protein, mitochondrial; 60 kDa chaperonin; Chaperonin 60; CPN60; Heat shock protein 60; HSP-60; Hsp60; HuCHA60; Mitochondrial matrix protein P1; P60 lymphocyte protein; HSPD1; HSP60

Immunogen: Purified recombinant human Hsp60 protein fragments expressed in E.coli.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: