HSP90 Antibody | 5858

Heat shock proteins (HSPs) are ubiquitously expressed in all organisms. A major function of HSP90 and other HSPs is to act as molecular chaperones. HSP90 forms a complex with glucocorticoid receptor (GR), rendering the non-ligand-bound receptor transcriptionally inactive. HSP 90 binds the GR as a heterocomplex composed of either HSP56 or cyclophilin-40, forming an aporeceptor complex. HSP90 also exists as a dimer with other proteins such as p60/sti1 and p23, forming an aporeceptor complex with estrogen and androgen receptors.

5858 | HSP90 Antibody DataSheet

Antibody Target: HSP90

Target Alternative Name: Heat shock 90 kDa protein 1A/1B, Heat shock 90 kDa protein 1/2, HSP90-1/HSP90-2, HSPA1A, HSPA1, HSPA1B

Tag Line:

Category: HSP90

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human, mouse, rat.

Immunogen Sequence: E. coli-expressed recombinant human HSP90

Accession #: P08238

Gene ID: 3326

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 200 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, 0.5 mM EDTA and 0.03 % ProClin®

Purification: Affinity purified

Application: Western blot, immunoprecipitation, immunohistochemistry.

Positive Control:

Application And Usages: The antibody can be used in Western blotting (0.5-4 µg/ml). Based on researchers feed back, the antibody also works well in immunoprecipitation (10-20 µg/ml) and immunohistochemistry (frozen sections, 10-20 µg/ml). However, the optimal concentrations should be determined individually.

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified:

Flow Cytometry Verified: Not Verified