HTATIP2 Antibody | 27-700

HTATIP2 Antibody | 27-700 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Dog

Homology: N/A

Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HTATIP2.

Research Area: Transcription, Cancer, Apoptosis

Tested Application: E, WB, IHC

Application: HTATIP2 antibody can be used for detection of HTATIP2 by ELISA at 1:1562500. HTATIP2 antibody can be used for detection of HTATIP2 by western blot at 0.5-1.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.

Specificiy: N/A

Positive Control 1: Cat. No. 1205 - Jurkat Cell Lysate

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: 27 kDa

Validation: N/A

Isoform: N/A

Purification: Antibody is supplied as total IgG.

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Concentration: batch dependent

Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store HTATIP2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.

Alternate Name: HTATIP2, CC3, TIP30, SDR44U1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CC3 (HTATIP2) is a member of the short-chain dehydrogenases/reductases (SDR) family. It is a novel serine/threonine kinase that phosphorylates the C-terminal domain (CTD) of the largest RNA polymerase II subunit and induces the expression of apoptosis related genes Bad and Siva, as well as metastasis suppressor NM23-H2. It also interacts with an estrogen receptor alpha-interacting coactivator CIA and regulates ERalpha-mediated c-myc transcription.