HTRA1 Polyclonal Antibody | E-AB-53300

HTRA1 Polyclonal Antibody | E-AB-53300 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: ARMD7, CARASIL, High-temperature requirement A serine peptidase 1, HtrA, HtrA serine peptidase 1, HTRA1, HTRA1, IGFBP5 protease, L56, ORF480, Protease serine 11 (IGF binding), protease serine 11, PRSS11 , Serine protease 11, Serine protease HTRA1, Serine protease HTRA1 precursor

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Signal transduction

Background: This gene encodes a member of the trypsin family of serine proteases. This protein is a secreted enzyme that is proposed to regulate the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. It has also been suggested to be a regulator of cell growth. Variations in the promoter region of this gene are the cause of susceptibility to age-related macular degeneration type 7.

Concentration: 0.9 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human HTRA1

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Purification Method: Antigen affinity purification

Dilution: WB 1:500-1:2000, IHC 1:40-1:200, ELISA 1:5000-1:10000

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 51 kDa

Molecular Weight(Observed): Refer to figures