Human Alpha-Synuclein | P1620

Alpha-Synuclein is a neuronal protein that plays an important role in presynaptic signaling and membrane trafficking. It is a soluble, natively unfolded protein with an extended structure primarily composed of random coils. It aggregates and interacts with other proteins such as synphilin-1, to induce neuronal cell toxicity in Parkinson's disease.

P1620 | Human Alpha-Synuclein DataSheet

Biomolecule/Target :

Synonyms: SNCA; Non-A beta component of AD amyloid; NACP; PARK1; PARK4; Non-A4 component of amyloid precursor; PD1

Alternates names: SNCA; Non-A beta component of AD amyloid; NACP; PARK1; PARK4; Non-A4 component of amyloid precursor; PD1

Taglines: A neuronal protein

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Human

Accession #: P37840, NP_000336

Recombinant: TRUE

Source: E.coli

Purity by SDS-PAGE: ≥ 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 1 EU/ug of protein as determined by LAL method

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 14.4 kDa

Concentration: 1 mg/ml (determined by BCA assay)

Appearance: Liquid

Physical form description:

Reconstitution Instructions:

Amino acid sequence: aa 1-140

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans