Human BMP-2 protein | PRP100126

Human BMP-2 protein | PRP100126 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.

Activity: Measured by its ability to induce alkaline phosphatase production by MC3T3-E1 mouse osteoblastic cells. The ED50 for this effect is typically 0.5-2 μg/ml.

protein Lenght: The recombinant human BMP2 monomer consists of 115 amino acids and has a predicted molecular mass of 13 kDa.

Preparation: E. coli

Purity: > 95 % as determined by SDS-PAGE

Formulation: Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.

Kit Component: N/A

Features & Benefits : N/A

Molecular Weight: 13 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human BMP-2 protein in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human BMP-2 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.43% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF β signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

Alternative Names: BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2

Search Names: BDA2; BDA2A; BMP-2; BMP2A; Bone morphogenetic protein 2; BMP2

Tag: BMP-2