Human Carcinoembryonic Antigen | P1712

The carcinoembryonic antigen (CEA) protein is a cell surface glycoprotein. CEA plays a role as an oncogene by promoting tumor progression through its modulation of cell adhesion and intracellular signaling, and inducing resistance to anoikis of colorectal carcinoma cells. CEA is therefore useful as a clinical biomarker for gastrointestinal cancers.

P1712 | Human Carcinoembryonic Antigen DataSheet

Biomolecule/Target :

Synonyms: CEA Cell Adhesion Molecule 5; Carcinoembryonic antigen-related cell adhesion molecule 5; Meconium antigen 100; CD66e; CEA; carcinoembryonic antigen; CD66e antigen; CEACAM5

Alternates names:

Taglines: Potential oncogene that modulates cell adhesion; native protein isolated from human liver metastases

NCBI Gene ID #: 1048

NCBI Gene Symbol:

Gene Source: Human

Accession #: P06731

Recombinant: False

Source: Human liver metastases

Purity by SDS-PAGE: ≥ 95% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity: Activity verified by Accubind ELISA

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 77 kDa predicted; 180 kDa observed (due to extensive glycosylation)

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized powder

Reconstitution Instructions: Reconstitute using neutral pH buffer of choice

Amino acid sequence: Full length native protein

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans