Human CD226/DNAM-1 protein, His tag (Animal-Free) | PRP2038

Human CD226/DNAM-1 protein, His tag (Animal-Free) | PRP2038 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines (Animal-Free)

Sequence: Amino acid sequence derived from human CD226 protein (NP_006557, Met 1-Asn 247) was expressed with a polyhistidine tag at the C-terminus.

Activity: N/A

protein Lenght: The recombinant human CD226 protein consists of 236 amino acids and predicts a molecular mass of 27 kD.The apparent molecular mass of the human CD226 is approximately 36-50 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Preparation: HEK 293 Cells

Purity: >95% as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS, pH 7.4.

Kit Component: N/A

Features & Benefits : Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 27kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD226 protein in the buffer which we provide not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human CD226/DNAM-1 protein, His tag (Animal-Free) should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.117% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: The adhesion receptor CD226 (DNAM-1) is a member of the Ig superfamily possessing two extracellular V-like domains. In humans, CD226 was shown to be expressed by NK as well as T cells. During T cell priming, CD226-mediated costimulatory signals may skew the subsequent differentiation into the Th1 pathway. In addition, CD226 expressed on NK and cytotoxic T cells is engaged by its counter-receptor CD155, present on target cells, thereby triggering their elimination.CD226 represents receptor-activating cytotoxic T lymphocyte and natural killer cells taking part in tumor surveillance, the pathogenesis of inflammation, and autoimmune disorders.

Alternative Names: CD226 antigenplatelet and T cell activation antigen 1; CD226 molecule; CD226; DNAM1; DNAM-1; DNAM1adhesion glycoprotein; DNAM-1DNAX accessory molecule-1; DNAX accessory molecule 1; PTA1; T lineage-specific activation antigen 1 antigen; TLiSA1

Search Names: CD226 antigenplatelet and T cell activation antigen 1; CD226 molecule; CD226; DNAM1; DNAM-1; DNAM1adhesion glycoprotein; DNAM-1DNAX accessory molecule-1; DNAX accessory molecule 1; PTA1; T lineage-specific activation antigen 1 antigen; TLiSA1

Tag: CD226/DNAM-1