Human CD84/SLAMF5 protein, His tag (Animal-Free) | PRP2037

Human CD84/SLAMF5 protein, His tag (Animal-Free) | PRP2037 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines (Animal-Free)

Sequence: Amino acid sequence derived from human CD84 protein (NP_003865.1, Met1-Gly225) was expressed with a polyhistidine tag at the C-terminus.

Activity: N/A

protein Lenght: The recombinant human CD84 protein consists of 214 amino acids and predicts a molecular mass of 24 kD.The apparent molecular mass of the human CD84 is approximately 40-53 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Preparation: HEK 293 Cells

Purity: >95% as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS, pH 7.4.

Kit Component: N/A

Features & Benefits : Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 24kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD84 protein in the buffer which we provide not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human CD84/SLAMF5 protein, His tag (Animal-Free) should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.116% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: CD84 (SLAMF5) is a member of the SLAM family of cell-surface immunoreceptors. Its cytoplasmic tail binds to Src homology 2 domain-containing protein 1A (signaling lymphocytic activation molecule-associated protein), a protein encoded by the X-linked lymphoproliferative disease gene.Broadly expressed on most immune cell subsets, CD84 functions as a homophilic adhesion molecule, whose signaling can activate or inhibit leukocyte function depending on the cell type and its stage of activation or differentiation. CD84-mediated signaling regulates diverse immunological processes, including T cell cytokine secretion, natural killer cell cytotoxicity, monocyte activation, autophagy, cognate T:B interactions, and B cell tolerance at the germinal center checkpoint.

Alternative Names: CD84 antigen (leukocyte antigen) ; CD84 antigen; CD84 molecule; CD84; Cell surface antigen MAX.3; DKFZp781E2378; hCD84; hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Ly-9B; mCD84; Signaling lymphocytic activation molecule 5; SLAM family member 5; SLAMF5; SLAMF5LY9B

Search Names: CD84 antigen (leukocyte antigen) ; CD84 antigen; CD84 molecule; CD84; Cell surface antigen MAX.3; DKFZp781E2378; hCD84; hly9-beta; leucocyte differentiation antigen CD84; leukocyte antigen CD84; Leukocyte differentiation antigen CD84; Ly-9B; mCD84; Signaling lymphocytic activation molecule 5; SLAM family member 5; SLAMF5; SLAMF5LY9B

Tag: CD84/SLAMF5