Human CellExp™ ANGPTL7 / CDT6, Human Recombinant | P1169

Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.

P1169 | Human CellExp ANGPTL7 / CDT6 Human Recombinant DataSheet

Biomolecule/Target: ANGPTL7

Synonyms: Angiopoietin-related protein 7, ANGPTL7, CDT6, Angiopoietin-like factor, Angiopoietin-like protein 7, Cornea-derived transcript 6 protein

Alternates names: APS, KLK2A1, PSA, Hk3, P-30 antigen, SemenoGelase

Taglines: Growth factor that enhance the expansion and engraftment of hematopoietic stem cells

NCBI Gene ID #: 354

NCBI Gene Symbol: KLK3

Gene Source: Human

Accession #: P07288

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): Measured by its binding ability in a functional ELISA.

Biological activity: Measured by its ability to cleave the colorimetric peptide substrate, Succinyl-Arg-Pro-Tyr-p-Nitroanilide (Suc-RPY-pNA). The specific activity is >100 pmoles/min/g

Results: >100 pmoles/min/g

Binding Capacity: Immobilized Human ANGPTL7, His Tag at 5 g/mL (100 L/well) can bind Human LILRB4, Fc Tag with a linear range of 0.031-0.5 g/mL Immobilized Human ANGPTL7, His Tag at 5 g/mL (100 L/well) can bind Human LILRB2, Fc Tag with a linear range of 0.031-2 g/mL Immobilized Human ANGPTL7, His Tag at 5 g/mL (100 L/well) can bind Human LILRA3, Fc Tag with a linear range of 0.016-1 g/mL

Unit Definition: N/A

Molecular Weight: 35 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Detailed reconstitution instructions are sent along with the product.

Amino acid sequence: N/A