Human CellExp™ Beta 2 Microglobulin | P1611

Beta 2 Microglobulin is a component of the class I major histocompatibility complex (MHC). It presents the antigenic peptides to the immune system. It is present in small amounts in serum, csf, and urine of normal people and to a much greater degree in the urine and plasma of patients with tubular proteinaemia, renal failure or kidney transplants. The levels of Beta 2 Microglobulin are increased in multiple myeloma. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions.

P1611 | Human CellExp™ Beta 2 Microglobulin DataSheet

Biomolecule/Target :

Synonyms: B2M

Alternates names: B2M

Taglines: A component of the class I major histocompatibility complex

NCBI Gene ID #: 567

NCBI Gene Symbol:

Gene Source: Human

Accession #: P61769

Recombinant: TRUE

Source: HEK293 cells

Purity by SDS-PAGE: ≥ 97% by SDSPAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 0.1 EU/ug of the protein as determined by LAL method

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: The protein migrates as a ~12-13 kDa band in SDS-PAGE

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized protein

Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water.

Amino acid sequence: aa Ile21-Met119

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans