Human CellExp™ BMP-2, Human Recombinant | 6444

BMP2 belongs to the transforming growth factor-beta (TGF) superfamily. As implied by their name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. In addition to its osteogenic activity, BMP-2 also plays an important role in cardiac morphogenesis. BMP-2 is expressed in a variety of tissues such as lung, spleen, brain, liver, prostate ovary, and small intestine. BMP2 is a candidate gene for the autosomal dominant disease of fibrodysplasia (myositis) ossificans progressiva. ’s BMP-2 is produced in a serum-free, chemically defined media. Production in human 293 cells offers authentic glycosylation, contributing to stability in cell growth media and other applications.

6444 | Human CellExp BMP-2 Human Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: Human Cellexp Human Recombinant BMP-2

Alternates names: Proepithelin; PEPI; PC Cell-derived Growth Factor

Taglines: A protein involved in the hedgehog and TGF beta signaling pathway

NCBI Gene ID #: 10116

NCBI Gene Symbol: GRN

Gene Source: Human

Accession #: P23785

Recombinant: Yes

Source: Human 293 cell expressed

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~65.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from a solution of 50 mM sodium acetate, pH 4.5, with 50 mM NaCl.

Reconstitution Instructions: Reconstitute in dH2O before use.

Amino acid sequence: Signal peptide and rat Progranulin (aa 1-602) fused at the C-terminus to a FLAG®-tag.