Human CellExp™ CD177 | P1604

CD177 is a glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein. CD177 contains two UPAR/Ly6 domains. CD177 is highly expressed in normal bone marrow and weakly expressed in fetal liver. Neutrophil-specific CD177 is a heterophilic binding partner of PECAM-1 (platelet endothelial cell adhesion molecule-1). This interaction mediates neutrophil transmigration.

P1604 | Human CellExp™ CD177 DataSheet

Biomolecule/Target :

Synonyms: HNA-2a, PRV-1, N B1, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, Human neutrophil alloantigen 2a

Alternates names: HNA-2a, PRV-1, N B1, NB1 GP, NB1 glycoprotein, Polycythemia rubra vera protein 1, Human neutrophil alloantigen 2a

Taglines: A glycosyl-phosphatidylinositol (GPI)-linked N-glycosylated cell surface glycoprotein

NCBI Gene ID #: 57126

NCBI Gene Symbol:

Gene Source: Human

Accession #: Q8N6Q3

Recombinant: TRUE

Source: HEK293 cells

Purity by SDS-PAGE: > 97% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level: < 0.1 EU/ug of the protein as determined by LAL method

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: Recombinant human CD177 protein migrates as a band at 90-100 kDa in SDS-PAGE

Concentration:

Appearance: Lyophilized protein

Physical form description: Lyophilized protein

Reconstitution Instructions: Reconstitute to a concentration of 0.1-0.5 mg/ml in sterile distilled water

Amino acid sequence: The target protein is expressed with the sequence (Met1-Gly407) of human CD177 (Accession #NP_065139.2.) fused with a Fc, 6×His tag at the C-terminus

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans