Human CellExp™ CD27 / TNFRSF7, Human recombinant | 9243

Platelet receptor Gi24, also known as B7-H5 and stress-induced secreted protein-1 (Sisp-1), is a protein that in humans is encoded by the C10orf54 gene, which contains 1 Ig-like (immunoglobulin-like) domain. As for C10orf54 gene, C10orf54 appears to positively interact with BMP-4, potentiating BMP signaling and the transition from an undifferentiated to a differentiated state on ESCs. Human C10orf54 undergoes proteolytic cleavage by MT1-MMP, generating a soluble 30 kDa extracellular fragment plus a 25-30 kDa membrane-bound fragment.

9243 | Human CellExp CD27 / TNFRSF7 Human recombinant DataSheet

Biomolecule/Target: CD27

Synonyms: CD27, TNFRSF7, S152, S152, LPFS2, T14, Tp56

Alternates names: INT-1, Proto-oncogene Int-1 homolog

Taglines: Member of Tumor necrosis factor receptor superfamily, play a role in survival of activated T-cells and in apoptosis through association with SIVA1.

NCBI Gene ID #: 7471

NCBI Gene Symbol: WNT1

Gene Source: Human

Accession #: P04628

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: >95%

Assay #2: N/A

Endotoxin Level: < 1 EU/g

Activity (Specifications/test method): N/A

Biological activity: The ED was determined by its ability to enhance BMP-2 induced alkaline phosphatase production by murine ATDC5 cells. The expected ED for this effect is 1.5 - 2.5 ng/ml in the presence of 200 ng/ml of human BMP-2.

Results: 1.5 - 2.5 ng/m

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 38.4 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 µg/µl. The solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A