Human CellExp™ CD30 /TNFRSF8, human recombinant | 7389

Human CD30, also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

7389 | Human CellExp CD30 /TNFRSF8 human recombinant DataSheet

Biomolecule/Target: CD30 /TNFRSF8

Synonyms: TNFRSF8, CD30, D1S166E, Ki-1

Alternates names: Collagen alpha-1(XVIII) chain, Endostatin-XV, Related to endostatin, Restin

Taglines: May play a role in the regulation of cellular growth and transformation of activated lymphoblasts

NCBI Gene ID #: 80781

NCBI Gene Symbol: COL18A1

Gene Source: Human

Accession #: P39060

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 20.5 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Generally 5-8% Mannitol or trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute with sterile dHO to a concentration 1.0 mg/ml, aliquot and store at below –20°C. Avoid freeze-thaw cycles.

Amino acid sequence: N/A