Human CellExp™ CD45, human recombinant | P1015

Protein tyrosine phosphatase, receptor type C (CD45), also known as PTPRC is a member of the protein tyrosine phosphatase (PTP) family which is known for its function to serve as signaling molecules and to regulate a variety of cellular processes such as cell proliferation, differentiation, mitotic cycle and oncogenic transformation. CD45 is found expression specifically in hemotopietic cells. CD45 consists of an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains. It serves as an essential regulator of T-cell and B-cell antigen receptor signaling through either direct interaction with components of the antigen receptor complexs or by activating various Src family kinases required for the antigen receptor signaling and it also can suppress JAK kinases.

P1015 | Human CellExp CD45 human recombinant DataSheet

Biomolecule/Target: PTPRC

Synonyms: LCA; LY5; B220; T200; CD45R; GP180; PTPRC

Alternates names: Growth hormone 1, Somatotropin, Pituitary growth hormone

Taglines: Receptor-type tyrosine-protein phosphatase C

NCBI Gene ID #: 2688

NCBI Gene Symbol: SOMA

Gene Source: Human

Accession #: P01241

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 5 EU/mg

Activity (Specifications/test method): N/A

Biological activity: 's pituitary Growth Hormone is fully biologically active when compared to World Health Organization (WHO) reference standard.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 22.367 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.2m-filtered solution in PBS.

Reconstitution Instructions: It is recommended to reconstitute the lyophilized hGH in 10 mM sodium phosphate buffer (pH 8.0) or 10 mM NH4HCO3 (pH 8.0). The solution can then be further diluted to other aqueous solutions. When diluting to below 10 ug/ml, the diluted solution should contain carrier protein (BSA or others) to avoid non-specific absorption of the hGH to plastic tubes.

Amino acid sequence: N/A