Human CellExp™ CD47, Fc Tag, Mouse Recombinant | P1390

Leukocyte surface antigen CD47 is also known as Antigenic surface determinant protein OA3, Integrin-associated protein (IAP) and Protein MER6. CD47 contains 1 Ig-like V-type (immunoglobulin-like) domain. CD47 is very broadly distributed on normal adult tissues. CD47 has a role in both cell adhesion by acting as an adhesion receptor for THBS1 on platelets, and in the modulation of integrins and plays an important role in memory formation and synaptic plasticity in the hippocampus by similarity. CD47 is the receptor for SIRPA, binding to which prevents maturation of immature dendritic cells and inhibits cytokine production by mature dendritic cells. CD47 Interaction with SIRPG mediates cell-cell adhesion, enhances superantigen-dependent T-cell-mediated proliferation and costimulates T-cell activation.

P1390 | Human CellExp CD47 Fc Tag Mouse Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: CD47, MER6, IAP, OA3

Alternates names: Growth hormone 1, Somatotropin, Pituitary growth hormone

Taglines: Plays a role in cell adhesion modulation of integrins

NCBI Gene ID #: 2688

NCBI Gene Symbol: SOMA

Gene Source: Murine

Accession #: P01241

Recombinant: FALSE

Source: HEK 293 cells

Purity by SDS-PAGEs: 98%

Assay: N/A

Purity: N/A

Assay #2: N/A

Endotoxin Level: Less than 0.1 EU per g by the LAL method.

Activity (Specifications/test method): Immobilized Mouse CD47, Mouse IgG2a Fc Tag at 10 g/mL (100 L/well) can bind Biotinylated Human SIRP alpha, Fc Tag with a linear range of 0.16-5 g/mL

Biological activity: 's pituitary Growth Hormone is fully biologically active when compared to World Health Organization (WHO) reference standard.

Results: N/A

Binding Capacity: Immobilized Mouse CD47, Mouse IgG2a Fc Tag at 10 g/mL (100 L/well) can bind Biotinylated Human SIRP alpha, Fc Tag with a linear range of 0.16-5 g/mL

Unit Definition: N/A

Molecular Weight: 22.367 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: It is recommended to reconstitute the lyophilized hGH in 10 mM sodium phosphate buffer (pH 8.0) or 10 mM NH4HCO3 (pH 8.0). The solution can then be further diluted to other aqueous solutions. When diluting to below 10 ug/ml, the diluted solution should contain carrier protein (BSA or others) to avoid non-specific absorption of the hGH to plastic tubes.

Amino acid sequence: N/A