Human CellExp™ CD58 /LFA-3, human recombinant | 7427

CD antigen CD58 is also known as Lymphocyte function-associated antigen 3 (LFA-3). CD58 is a cell adhesion molecule expressed on Antigen Presenting Cells (APC), particularly macrophages. CD58 /LFA3 is ligand of the T-lymphocyte CD2 glycoprotein, which binds to CD2 (LFA-2) on T cells and is important in strengthening the adhesion between the T cells and Professional Antigen Presenting Cells. In addition, the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells. Polymorphisms in the CD58 gene are associated with increased risk for multiple sclerosis.

7427 | Human CellExp CD58 /LFA-3 human recombinant DataSheet

Biomolecule/Target: CD58 /LFA-3

Synonyms: CD58, LFA3, Ag3

Alternates names: Insulin, INS

Taglines: N/A

NCBI Gene ID #: 3630

NCBI Gene Symbol: INS

Gene Source: Human

Accession #: P01308

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: The recombinant insulin is fully biologically active when compared to World Health Organization (WHO) reference standard which is 28 units/mg.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 5.81 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

Reconstitution Instructions: Reconstitute in H20 to a concentration of 1.0 mg/ml. The solution can then be diluted to other aqueous buffers.

Amino acid sequence: N/A