Human CellExp™ Complement Factor D, Human Recombinant | P1491

Complement factor D (CFD) is also known as Adipsin, C3 convertase activator, Properdin factor D (PFD), which contains one peptidase S1 domain and belongs to the peptidase S1 family. CFD / Adipsin cleaves factor B when the latter is complexed with factor C3b, activating the C3bbb complex, which then becomes the C3 convertase of the alternate pathway. CFD / Adipsin is a serine protease that stimulates glucose transport for triglyceride accumulation in fats cells and inhibits lipolysis. Defects in CFD / Adipsin are the cause of complement factor D deficiency which predisposes to invasive meningococcal disease.

P1491 | Human CellExp™ Complement Factor D, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: CFD, Adipsin, PFD, DF, Complement factor D

Alternates names: CFD, Adipsin, PFD, DF, Complement factor D

Taglines: Serine protease that stimulates glucose transport, inhibits lipolysis

NCBI Gene ID #: 1675

NCBI Gene Symbol: CFD

Gene Source: Human

Accession #: P00746-1

Recombinant: True

Source: HEK 293 cells

Purity by SDS-PAGE: >90%

Assay:

Purity:

Assay #2:

Endotoxin Level: Less than 1.0 EU per ug by the LAL method.

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.3 kDa. The protein migrates as 28 kDa under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.

Concentration:

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Amino acid sequence: AA Ile 26 - Ala 253

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans