Human CellExp™ Decorin /Bone proteoglycan II, human recombinant | 7449

Decorin, also known as bone proteoglycan II, PGS2, SLRR1B, DCN, DSPG2 and PG40, is a secreted chondroitin /dermatan sulfate proteoglycan in the family of small leucine-rich proteoglycans (SLRPs). Decorin is a small cellular or pericellular matrix proteoglycan and is closely related in structure to biglycan protein. Decorin and biglycan are thought to be the result of gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. Decorin appears to influence fibrillogenesis, and also interacts with fibronectin, thrombospondin, the complement component C1q, epidermal growth factor receptor (EGFR) and transforming growth factor-beta (TGF-beta). Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD).

7449 | Human CellExp Decorin /Bone proteoglycan II human recombinant DataSheet

Biomolecule/Target: Decorin /Bone proteoglycan II

Synonyms: Decorin, DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B.

Alternates names: Melanoma antigen recognized by T-cells 1, Protein Melan-A, Antigen SK29-AA, Antigen LB39-AA

Taglines: A protein which binds to type I collagen fibrils, and plays a role in matrix assembly

NCBI Gene ID #: 2315

NCBI Gene Symbol: MART-1

Gene Source: Human

Accession #: Q16655

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 18.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

Reconstitution Instructions: Reconstitute in HO to a concentration 0.1-1 mg/ml. The solution can then be further diluted to other aqueous solutions.

Amino acid sequence: N/A