Human CellExp™ DLL4, Mouse Recombinant | P1163

The Notch ligand delta-like protein 4 (DLL4) is expressed highly and selectively within the arterial endothelium and has been shown to function as a ligand for Notch1 and Notch4. It is induced by VEGF as a negative feedback regulator and acts to prevent overexuberant angiogenic sprouting, pro-moting the timely formation of a well differentiated vascular network. DLL4-Notch1 signaling regulates the formation of appropriate numbers of tip cells to control vessel sprouting and branching in the mouse retina.

P1163 | Human CellExp DLL4 Mouse Recombinant DataSheet

Biomolecule/Target: Dll4

Synonyms: Delta-like Protein 4, Delta 4

Alternates names: Melanoma antigen recognized by T-cells 1, Antigen LB39-AA, Antigen SK29-AA, MART-1, Melan-A

Taglines: Activates the Notch-1 and Notch-2 receptors

NCBI Gene ID #: 77836

NCBI Gene Symbol: Melan-A

Gene Source: Mouse

Accession #: Q2TA50

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGEs: N/A

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): Measured by inhibition of adipogenesis of 3T3L-1 cells

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 17.6 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: 0.2 m-filtered solution in PBS

Reconstitution Instructions: N/A

Amino acid sequence: N/A