Human CellExp™ Frizzled-5 / FZD5 Protein, Human recombinant | P1028

Frizzled5 (FZD5) is also known as FzE5, which belongs to the Gprotein coupled receptor Fz/Smo family. Most of frizzled receptors are coupled to the betacatenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK3 kinase, nuclear accumulation of betacatenin and activation of Wnt target genes. FZD5 contains one FZ (frizzled) domain. FZD5 may be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues. FZD5 interacts specifically with Wnt5A to induce the betacatenin pathway. FZD5 interacts with GOPC.

P1028 | Human CellExp Frizzled-5 / FZD5 Protein Human recombinant DataSheet

Biomolecule/Target: FZD5

Synonyms: FZD5, Frizzled-5, C2orf31, Fz-5, hFz5, FzE5

Alternates names: Heat Shock Protein 90, HSP90

Taglines: N/A

NCBI Gene ID #: 3326

NCBI Gene Symbol: HSP90AB1

Gene Source: Human

Accession #: P08238

Recombinant: Yes

Source: Sf9 cells

Purity by SDS-PAGEs: 99%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: Not available at this time

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 83.4 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.5. Generally Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: N/A

Amino acid sequence: MGSSHHHHHHSS GLVPRGSHMPEE VHHGEEEVETFP EEVHHGEEEVET FAFQAEIAQLMSL IINTFYSNKEIFLRE LISNASDALDKIRY ESLTDPSKLDSGK ELKIDIIPNPQERTL TLVDTGIGMTKAD LINNLGTIAKSGTK AFMEALQAGADIS MIGQFGVGFYSA YLVAEKVVVITKH NDDEQYAWESS AGGSFTVRADHG EPIGRGTKVILHL KEDQTEYLEERR VKEVVKKHSQFI GYPITLYLEKERE KEISDDEAEEEK GEKEEEDKDDEE KPKIEDVGSDEE DDSGKDKKKKTK KIKEKYIDQEELN KTKPIWTRNPDDI TQEEYGEFYKSL TNDWEDHLAVK HFSVEGQLEFRA LLFIPRRAPFDLF ENKKKKNNIKLY VRRVFIMDSCDE LIPEYLNFIRGVV DSEDLPLNISRE MLQQSKILKVIRK NIVKKCLELFSEL AEDKENYKKFYE AFSKNLKLGIHED STNRRRLSELLR YHTSQSGDEMT SLSEYVSRMKET QKSIYYITGESKE QVANSAFVERV RKRGFEVVYMT EPIDEYCVQQLK EFDGKSLVSVTK EGLELPEDEEEK KKMEESKAKFE NLCKLMKEILDKK VEKVTISNRLVSS PCCIVTSTYGWT ANMERIMKAQAL RDNSTMGYMMA KKHLEINPDHPIVE TLRQKAEADKNDK AVKDLVVLLFETALL SSGFSLEDPQTH SNRIYRMIKLGLG IDEDEVAAEE PNAAVPDEIPPLEG DEDASRMEEVD