Human CellExp™ Human Serum Albumin, Human Recombinant | P1493

serum albumin (SA) is also known as ALB, which is the main protein of plasma and has a good binding capacity for water,Ca2+,Na+,K+,fatty acids,hormones, bilirubin and drugs.The main function of SA is the regulation of the colloidal osmotic pressure of blood. As Major zinc transporter in plasma, SA typically binds about 80% of all plasma zinc. A variant structure of albumin could lead to increased binding of zinc resulting in an asymptomatic augmentation of zinc concentration in the blood. Defects in serum albumin can cause familial dysalbuminemic hyperthyroxinemia which is a form of euthyroid hyperthyroxinemia that is due to increased affinity of serum albumin for T4. It is the most common cause of inherited euthyroid hyperthyroxinemia in Caucasian population.

P1493 | Human CellExp™ Human Serum Albumin, Human Recombinant DataSheet

Biomolecule/Target :

Synonyms: Serum albumin, ALB, Alb

Alternates names: Serum albumin, ALB, Alb

Taglines: A human blood plasma protein involved in transport of hormones/fatty acids

NCBI Gene ID #: 213

NCBI Gene Symbol: ALB

Gene Source: Human

Accession #: P02768

Recombinant: True

Source: HEK 293 cells

Purity by SDS-PAGE: >95%

Assay:

Purity:

Assay #2:

Endotoxin Level: Less than 1.0 EU per ug by the LAL method.

Activity (Specifications/test method): Immobilized Biotinylated Human FCGRT&B2M Heterodimer Protein, Avitag,His Tag&Strep II Tag (SPR & BLI verified) on SA Chip can bind Human Serum Albumin, His Tag, low endotoxin with an affinity constant of 1.46 uM as determined in a SPR assay

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 67.3 kDa. The protein migrates as 67-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Concentration:

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute in sterile deionized water to the desired protein concentration.

Amino acid sequence: AA Asp 25 - Leu 609

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans