Human CellExp™ ICAM2 /CD102, human recombinant | 7487

Intercellular adhesion molecule 2 (ICAM2) is also known as CD antigen CD102, which belongs to the immunoglobulin superfamily and ICAM family. ICAM2 contains two Ig-like C2-type (immunoglobulin-like) domains. ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 / CD102 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response; NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance.

7487 | Human CellExp ICAM2 /CD102 human recombinant DataSheet

Biomolecule/Target: ICAM2 /CD102

Synonyms: ICAM2, CD102, Intercellular adhesion molecule 2

Alternates names: BMPR-1A, BMP-R1A, BMPR1A, BMR1A, CD292, CD-292, Activin receptor-like kinase 3, Serine/threonine-protein kinase receptor R5, CD_antigen=CD292

Taglines: Plays a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion

NCBI Gene ID #: 657

NCBI Gene Symbol: BMPR1A

Gene Source: Human

Accession #: P36894

Recombinant: Yes

Source: Insect cells (Baculovirus)

Purity by SDS-PAGEs: 90%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Measured by its ability to inhibit recombinant human BMP-2 induced alkaline phosphatase production by C2C12 myogenic cells. The ED for this effect is typically 1-3 µg/ml in the presence of 500 ng/ml of recombinant human BMP-2.

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 23.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose is added as protectants before lyophilization.

Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in sterile PBS to a concentration 100 µg/ml. This solution can then be diluted into other aqueous buffers.

Amino acid sequence: N/A