Human CellExp™ IGFBP-7, Human Recombinant | P1212

Insulin-like growth factor-binding protein 7 (IGFBP7) is also known as IGFBP-rP1, MAC25 protein, PGI2-stimulating factor, prostacyclin-stimulating factor and tumor-derived adhesion factor, which contains one Ig-like C2-type (immunoglobulin-like) domain, one IGFBP N-terminal domain and one Kazal-like domain. The major function of IGFBP7 is the regulation of availability of insulin-like growth factors (IGFs) in tissue as well as in modulating IGF binding to its receptors. IGFBP7 binds to IGF with high affinity except for IGF-I and IGF-II.IGFBP7 also stimulates cell adhesion. Furthermore, IGFBP7 is implicated in some cancers

P1212 | Human CellExp IGFBP-7 Human Recombinant DataSheet

Biomolecule/Target: IGFBP7

Synonyms: Insulin-like growth factor-binding protein 7, IGFBP7, IGF-binding protein 7, IGFBP-rP1, MAC25 protein, Tumor-derived adhesion factor, TAF

Alternates names: pS2 protein, HP1.A, Breast Cancer Estrogen-Inducible protein (BCEI), PNR2, Breast cancer estrogen-inducible protein, PNR-2, Polypeptide P1.A, Protein pS2

Taglines: Plays a role in skeletal myogenesis by binding to IGF

NCBI Gene ID #: 7031

NCBI Gene Symbol: TFF1

Gene Source: Human

Accession #: P04155

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): N/A

Biological activity: Determined by its ability to chemoattract human MCF-7 cells using a concentration 5-10 g/ml.

Results: 5-10 g/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 8.2 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization.

Reconstitution Instructions: Reconstitute in HO to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A