Human CellExp™ IL-29, Human Recombinant | 6473

IL-29 is distantly related to type I interferons and the IL-10 family. Expression of IL-29 is induced by viral infection which interacts with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor (IL10RB) and interleukin 28 receptor . IL-29 exhibits common features with type I IFNs such as antiviral activity, antiproliferative activity and in vivo antitumor activity. IL-29 acts similarly to IFNs, but is less effective generally and has activity in a more limited range of cell lines. IL-29 produced in response to viral infection, activates both monocytes and macrophages producing a restricted panel of cytokines and therefore is an important factor in activating innate immune responses at the site of viral infection. IFN-Lambda 1 antiviral and antiproliferative activity requires Interferon-Lambda 2 receptor tyrosine residues.

6473 | Human CellExp IL-29 Human Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: Human Cellexp Human Recombinant IL-29

Alternates names: Hsc70-interacting protein, Suppression of tumorigenicity 13 protein, Putative tumor suppressor ST13, FAM10A1, Progesterone receptor-associated p48 protein, Renal carcinoma antigen NY-REN-33

Taglines: A cytokine mediating adaptive immune response

NCBI Gene ID #: 6767

NCBI Gene Symbol: ST13

Gene Source: Human

Accession #: P50502

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 99%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 43 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized in PBS.

Reconstitution Instructions: N/A

Amino acid sequence: N/A