Human CellExp™ Integrin alpha 6 beta 1 Heterodimer, Human Recombinant | P1203

Integrin alpha 6 beta 1, also called platelet glycoprotein GPIc-IIa, is a receptor for laminin on platelets. The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. ITGA6 has been shown to interact with TSPAN4 and GIPC1.

P1203 | Human CellExp Integrin alpha 6 beta 1 Heterodimer Human Recombinant DataSheet

Biomolecule/Target: ITGA6, ITGB1

Synonyms: Integrin alpha 6 beta 1, ITGA6B1, ITGA6&ITGB1, CD49f, VLA-6

Alternates names: Nicotinamide phosphoribosyltransferase, Pre-B-cell colony-enhancing factor 1 homolog, NAmPRTase, Nampt, PBEF

Taglines: Hetrodimer integrin (alpha 6 beta 1) negatively regulate erbB2/HER2 signaling

NCBI Gene ID #: 297508

NCBI Gene Symbol: NAMPT

Gene Source: Rat

Accession #: Q80Z29

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method):

Biological activity: Amino acids 1 to 491 (per UniProt Q80Z29)

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 53.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH7.4. Normally trehalose is added as protectant before lyophilization.

Reconstitution Instructions: Reconstitute in PBS to the concentration of 0.1-1 mg/ml.

Amino acid sequence: Amino acids 1 to 491 (per UniProt Q80Z29)