Human CellExp™ LAG-3 / CD223, Cynomolgus Recombinant | P1179

Lymphocyte activation gene 3 protein (LAG3) is also known as CD antigen CD223 and protein FDC, which belongs to immunoglobulin (Ig) superfamily and contains 4 extracellular Ig-like domains. The LAG3 gene contains 8 exons. The sequence data, exon/intron organization, and chromosomal localization all indicate a close relationship of LAG3 to CD4. LAG3 /CD223 involved in lymphocyte activation. LAG3 /CD223 binds to HLA class-II antigens.

P1179 | Human CellExp LAG-3 / CD223 Cynomolgus Recombinant DataSheet

Biomolecule/Target: LAG3

Synonyms: LAG3, CD223, FDC

Alternates names: Nesfatin 1, Nucleobindin-2, DNA-binding protein NEFA, Prepronefastin

Taglines: A protein involved in lymphocyte activation

NCBI Gene ID #: 53322

NCBI Gene Symbol: Nucb2

Gene Source: Mouse

Accession #: P81117

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per/g

Activity (Specifications/test method): N/A

Biological activity: Not available at this time

Results: N/A

Binding Capacity: Immobilized Cynomolgus LAG-3, mouse IgG2a Fc tag at 2 g/mL (100 l/well) can bind Anti-LAG3 MAb,Human IgG1 with a linear range of 3-20 ng/ml.

Unit Definition: N/A

Molecular Weight: 8.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization.

Reconstitution Instructions: Reconstitute with sterile HO to a concentration of 0.1-1 mg/ml. Further dilutions should be made with medium containing 0.2% BSA.

Amino acid sequence: N/A