Human CellExp™ Lipoprotein Lipase, Human Recombinant | P1309

LPL is a lipoprotein lipase, which is expressed in the heart, muscle, and adipose tissue. LPL acts as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Type I hyperlipoproteinemia is a result of severe mutations which cause LPL deficiency, whereas less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. Lipoprotein lipase (LPL) is a fundamental enzyme in plasma triglyceride hydrolysis and is secreted by macrophages in the subendothelial space. LPL also promotes the development of atherosclerosis through facilitation of monocyte adhesion to endothelial cells, stimulation of tumor necrosis factor alpha (TNF) secretion and induction of vascular smooth muscle cell proliferation.

P1309 | Human CellExp Lipoprotein Lipase Human Recombinant DataSheet

Biomolecule/Target: LPL

Synonyms: Lipoprotein lipase, LPL, LIPD, HDLCQ11

Alternates names: Lipoprotein lipase, LPL, LIPD, HDLCQ11

Taglines: Involved in the hydrolysis of triglycerides of circulating chylomicrons and very low density lipoproteins

NCBI Gene ID #: 116562

NCBI Gene Symbol: IL2

Gene Source: Human

Accession #: P17108

Recombinant: Yes

Source: HEK 293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 51.8 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from (0.4 µm) filtered solution 0.5mg/ml in 20mM Tris buffer and 50mM NaCl, pH 7.5.

Reconstitution Instructions: Reconstitute in sterile deionized water to a concentration of 0.5 mg/ml

Amino acid sequence: N/A