Human CellExp™ M-CSF, Human Recombinant | 6455

Granulocyte/Macrophage Colony-Stimulating Factors (M-CSF) are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of granulocytes and monocytes-macrophages. M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. It also plays an important role in innate immunity and in inflammatory processes by promoting the release of proinflammatory chemokines. M-CSF is also required for normal bone development and male/female fertility.

6455 | Human CellExp M-CSF Human Recombinant DataSheet

Biomolecule/Target: M-CSF

Synonyms: Human Cellexp Human Recombinant M-CSF

Alternates names: Lipopolysaccharide-binding protein, LBP, LBP human recombinant protein, LBP human, human LBP

Taglines: A hematopoietic growth factor

NCBI Gene ID #: Mm.218846.

NCBI Gene Symbol: LBP

Gene Source: Mouse

Accession #: Q61805

Recombinant: Yes

Source: CHO cells

Purity by SDS-PAGEs: 95%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: < 1.0 EU per 1 g of protein

Activity (Specifications/test method): N/A

Biological activity: Up to 2 µg/ ml LBP mediates binding of FITC-LPS (0.5µg/ml) to CD14+CHO transfectants (2 x 106/ml)

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 64.0 kDa

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized from 0.22 m filtered PBS (pH 7.4) with 5% trehalose.

Reconstitution Instructions: Reconstitute in 10 µl of ultra-pure distilled water. This solution can then be diluted into other aqueous buffers and stored at –20°C or –70°C for future use.

Amino acid sequence: N/A