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Human CellExp™ Mucin-1/MUC-1, human recombinant | 8019
- SKU:
- 26-8019-GEN
- Availability:
- Usually shipped in 5 working days
Description
Mucin-1 (MUC1) is also known as Tumor-associated epithelial membrane antigen (EMA), Polymorphic epithelial mucin (PEM), Peanut-reactive urinary mucin (PUM), PEMT, Krebs von den Lungen-6 (KL-6), CD antigen CD227, Episialin, H23AG. MUC1 is a glycoprotein with extensive O-linked glycosylation of its extracellular domain. Mucins line the apical surface of epithelial cells in the lungs, stomach, intestines, eyes and several other organs. Mucins protect the body from infection by pathogen binding to oligosaccharides in the extracellular domain, preventing the pathogen from reaching the cell surface. Except protective function by binding to pathogens, MUC1 also functions in a cell signaling capacity. Overexpression of MUC1 is often associated with colon, breast, ovarian, lung and pancreatic cancers.
8019 | Human CellExp Mucin-1/MUC-1 human recombinant DataSheet
Biomolecule/Target: Mucin-1/MUC-1
Synonyms: Mucin-1, MUC1, CD227, EMA, H23AG, KL-6, MAM6, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, CA 15-3, Episialin
Alternates names: Mucin-1, MUC1, CD227, EMA, H23AG, KL-6, MAM6, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM, CA 15-3, Episialin
Taglines: >95% Pure, Human cell expressed Mucin-1/MUC-1
NCBI Gene ID #: 3562
NCBI Gene Symbol: IL3
Gene Source: Human
Accession #: P08700
Recombinant: Yes
Source: HEK 293 cells
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: < 1.0 EU per g of the protein by the LAL method.
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: This protein is fused with a human IgG1 Fc tag at the C-terminus, and has a calculated MW of 51.3 kDa. The predicted N-terminus is Ser 33. DTT-reduced Protein migrates as 45-66 kDa in SDS-PAGE due to glycosylation.
Concentration: N/A
Appearance: Lyophilized
Physical form description: Lyophilized from 0.22 m filtered solution in PBS, pH 7.4. Normally Mannitol or Trehalose are added as protectants before lyophilization.
Reconstitution Instructions: Centrifuge the vial prior to opening. Reconstitute in PBS, pH 7.4. Do not vortex.
Amino acid sequence: N/A