Human CellExp™ Netrin-1, human recombinant | 7575

Netrin-1 controls guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Netrin-1 is also Involved in tumorigenesis by regulating apoptosis.

7575 | Human CellExp Netrin-1 human recombinant DataSheet

Biomolecule/Target: Netrin-1

Synonyms: NTN1

Alternates names: NTN1

Taglines: Involved in tumorigenesis by regulating apoptosis.

NCBI Gene ID #: 16187

NCBI Gene Symbol: IL3

Gene Source: Human

Accession #: P01586

Recombinant: Yes

Source: HEK293 cells

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <0.1 EU/g by LAL method

Activity (Specifications/test method): Induces axon outgrowth.

Biological activity: Induces axon outgrowth.

Results: Induces axon outgrowth.

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: ~80.0 kDa. Human netrin-1 (aa 25-604) is fused at the C-terminus to a FLAG®-tag.

Concentration: N/A

Appearance: Lyophilized

Physical form description: Lyophilized in PBS with trehalose and Brij 35.

Reconstitution Instructions: Reconstitute with 100 l sterile distilled water.

Amino acid sequence: N/A