Human CellExp™ RBP4, rat recombinant | 7566

Retinol binding protein 4 (RBP4; RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity, and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.

7566 | Human CellExp RBP4 rat recombinant DataSheet

Biomolecule/Target: RBP4

Synonyms: Retinol Binding Protein 4, Plasma retinol-binding protein, PRBP, RBP

Alternates names: Phenylpyruvate tautomerase, Glycosylation-inhibiting factor, GIF, MMIF, MIF, Glycosylation-inhibiting factor, L-dopachrome isomerase, L-dopachrome tautomerase, Phenylpyruvate tautomerase.

Taglines: The primary transporter of retinol (vitamin A) to tissues and an adipokine linking GLUT4 suppression in adipose tissue to insulin

NCBI Gene ID #: 4282

NCBI Gene Symbol: MIF

Gene Source: Human

Accession #: P14174

Recombinant: Yes

Source: E. coli

Purity by SDS-PAGEs: 97%

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: <0.1 EU/g by LAL method

Activity (Specifications/test method): N/A

Biological activity: Human MIF biological activity was measured in an agarose micro droplet assay using human U937 cells as targets. The optimal range of activity found for human MIF in this assay was 0.5-1µg/ml.

Results: 0.5-1µg/ml

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 12.5 kDa

Concentration: N/A

Appearance: Liquid

Physical form description: 0.2 m-filtered solution in PBS, pH 7.2.

Reconstitution Instructions: Reconstitute in sterile dHO to a concentration of 0.1 -1 mg/ml. This solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.

Amino acid sequence: N/A