Human CellExp™ SARS-CoV-2 Spike RBD (E484K) | P1649

SARS-CoV-2 Spike protein is a large type I transmembrane protein composed of S1 subunit and S2 subunit. During viral infection, the receptor-binding domain (RBD) of the S1 subunit is responsible for the recognition and binding of host receptor ACE2, while the S2 subunit mediates viral cell membrane fusion. The SARS-CoV-2-S1-RBD/ACE2 interaction mediates viral entry into the target cells. The E484K mutant mildly increase receptor binding.

P1649 | Human CellExp™ SARS-CoV-2 Spike RBD (E484K) DataSheet

Biomolecule/Target :

Synonyms: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein

Alternates names: COVID-19 Spike RBD protein (E484K); 2019-nCoV Spike RBD protein (E484K); SARS-CoV-2 Mutant (E484K); SARS-CoV-2 (E484K) mutant protein

Taglines: Spike RBD variant with E84k mutation which mildly increase receptor binding

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Coronavirus

Accession #: YP_009724390.1

Recombinant: 1

Source: Hek293

Purity by SDS-PAGE: ≥ 90% by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: 35 kDa

Concentration:

Appearance: Lyophilized protein

Physical form description:

Reconstitution Instructions: Reconstitute in sterile water to a concentration of 1 mg/ml.

Amino acid sequence: The target protein SARS-CoV-2 S Protein RBD (E484K) is expressed with His tag at the C-terminus.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans