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Human CellExp™ TNF-alpha Extracellular Domain, Human Recombinant | P1392

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SKU:
26-P1392-GEN
Availability:
Usually shipped in 5 working days
NULL388.00 - NULL1,043.00

Description

Tumor Necrosis Factor- (TNF-) is a highly pleiotropic cytokine with multiple activities other than its originally discovered role of tumor necrosis in rodents. It contributes to both inflammations during infections and anti-inflammatory/tissue repair processes after clearance of infection. TNF- is mainly produced by activated macrophages, T lymphocytes, and natural killer (NK) cells. The activity of TNF- is mediated through two cell surface receptors, TNF-R1 (p55) and TNF-R2 (p75) that differ in their signaling activity. TNF-'s primary role is in the regulation of immune cells. It can induce cell death of certain tumor cell lines. About 28% of cancers are susceptible to direct cell killing mediated by soluble TNF-.

P1392 | Human CellExp TNF-alpha Extracellular Domain Human Recombinant DataSheet

Biomolecule/Target: N/A

Synonyms: TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Cachectin, DIF, TNFA, TNFSF2

Alternates names: E-GFP, Enhanced Green Fluorescent Protein

Taglines: A potent cytokine exerting cytotoxic effects on a wide range of cells

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source:

Accession #: P42212

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGEs:

Assay: SDS-PAGE

Purity: N/A

Assay #2: N/A

Endotoxin Level: N/A

Activity (Specifications/test method): N/A

Biological activity: N/A

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 32.7 kDa

Concentration: N/A

Appearance: Lyophilized powder

Physical form description: Lyophilized

Reconstitution Instructions: Reconstitute with PBS to 1 mg/ml

Amino acid sequence: N/A

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Additional Information

Storage:
-20°C
Shipping:
Gel Pack
Shelf Life:
12 months
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