Human FLT3L protein, His Tag | PRP100087

Human FLT3L protein, His Tag | PRP100087 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from human FLT3LG (P49771-1) (Thr27-Pro185) was expressed, with a polyhistidine tag at the N-terminus.

Activity: Measured in a cell proliferation assay using BaF3 mouse pro­B cells transfected with mouse Flt­3. The ED50 for this effect is typically 2-11 ng/mL.

protein Lenght: The recombinant human human FLT3LG consists of 175 amino acids and predicts a molecular mass of 20.2 KDa. It migrates as an approximately 27 KDa band in SDS-PAGE under reducing conditions.

Preparation: Baculovirus-Insect Cells

Purity: > 95 % as determined by SDS-PAGE

Formulation: Lyophilized from sterile 20mM Tris, 500mM NaCl, pH 7.4

Kit Component: N/A

Features & Benefits : N/A

Molecular Weight: 20.2 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human Flt3 ligand protein, His Tag in sterile ddH2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human FLT3L protein, His Tagshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.38% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of the hematopoietic progenitors and stem cells. This may help the system to kill cancer cells. Dendritic cells (DCs) provide the key link between innate and adaptive immunity by recognizing pathogens and priming pathogen-specific immune responses. FLT3L controls the development of DCs and is particularly important for plasmacytoid DCs and CD8 -positive classical DCs and their CD103 -positive tissue counterparts.

Alternative Names: FL; FLT3L; FLT3LG; Fms-related tyrosine kinase 3 ligand; FLT3LG

Search Names: FL; FLT3L; FLT3LG; Fms-related tyrosine kinase 3 ligand; FLT3LG

Tag: FLT3L