Human IL-36γ protein | PRP1029

Human IL-36γ protein | PRP1029 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from Human IL-36γ (Q9NZH8) (Ser18-Asp169) was expressed.

Activity: N/A

protein Lenght: The recombinant Human IL-36-gamma consists of 152 amino acids and has a predicted molecular mass of 16.7 kDa.

Preparation: E. coli

Purity: >98% as determined by SDS-PAGE

Formulation: Lyophilized from sterile 20 mM tris 50 mM NaCl, pH 6.5.

Kit Component: N/A

Features & Benefits : Endotoxin: <1 EU per µg of the protein as determined by the LAL method.

Molecular Weight: 16.7 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL36-gamma protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human IL-36γ proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.106% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: The IL-1 family is comprised of 11 structurally related ligands, including recently re-named IL-36 α (IL-1F6), β (IL-1F8) and γ (IL-1F9) . IL-36γ is highly expressed in psoriatic plaques and in tissues containing epithelial cells. IL-36γ signals through the IL-1Rrp2 (IL-1R6) receptor, which is primarily expressed on certain dendritic cells. The interaction of the IL-1Rrp2 receptor with IL-36 ligands induces dendritic cell maturation and activation. IL-36γ also functions as an agonist of NF-κB, and can stimulate the inflammatory response in bronchial epithelial cells.

Alternative Names: Interleukin 36 GammaInterleukin-1 Homolog 1;Interleukin-1 Epsilon;IL-1RP2;IL-1F9 ;IL-1H1 ;IL1H1;IL1E;Interleukin 1-Related Protein 2 ;Interleukin-36 Gamma;IL1RP2;IL1F9

Search Names: Interleukin 36 GammaInterleukin-1 Homolog 1;Interleukin-1 Epsilon;IL-1RP2;IL-1F9 ;IL-1H1 ;IL1H1;IL1E;Interleukin 1-Related Protein 2 ;Interleukin-36 Gamma;IL1RP2;IL1F9

Tag: IL-36γ