Human IL-4 protein | PRP2017

Human IL-4 protein | PRP2017 | Gentaur UK, US & Europe Distribution

Product Category: Cytology

Application: Cytokines

Product Type: Cytokines

Sequence: Amino acid sequence derived from Human IL-4 protein isoform (P05112，Met 1-Ser153) was expressed.

Activity: Testing in progress.

protein Lenght: The recombinant Human IL-4 protein consists of 133 amino acids and has a predicted molecular mass of 15.4 kDa. The apparent molecular mass of the Human IL-4 protein is approximately 18 kDa in SDS-PAGE under reducing conditions.

Preparation: HEK293 Cells

Purity: ≥95 % as determined by SDS-PAGE

Formulation: Lyophilized from sterile PBS, pH 7.4.

Kit Component: N/A

Features & Benefits : N/A

Molecular Weight: 15.4 kDa

Usage Note: Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human IL-4 protein using the buffer we provided not less than 100 µg/mL, which can then be further diluted to other aqueous solutions.

Storage Conditions: Lyophilized Human IL-4 proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.129% HSA or BSA) . Please prevent freeze-thaw cycles.

Shipping: The product is shipped at ambient temperature.

Background: Interleukin-4 (IL-4), an anti-inflammatory cytokine, plays significant role in pathogenesis of various diseases such as asthma, tumors, and HIV infections. IL-4 is firstly identified as a T cell-derived growth factor for B cells. IL-4 can mediate important pro-inflammatory functions in asthma, including T helper cell type 2 lymphocyte differentiation, induction of IgE production, up-regulation of IgE receptors, expression of vascular cell-adhesion molecule 1, promotion of eosinophil transmigration into the lungs, inhibition of T-lymphocyte apoptosis, and mucus hypersecretion. The role of IL-4 in the pathogenesis of asthma is supported by identification of polymorphisms linked to asthma in the IL-4 gene promoter and proteins involved in IL-4 signaling.

Alternative Names: IL4; IL-4; IL-4B_cell stimulatory factor 1;B cell growth factor 1; BCGF1; BCGF-1; interleukin 4; binetrakin; BCDF; B-cell stimulatory factor 1; BSF1; BSF-1; IL4E12; interleukin-4; Lymphocyte stimulatory factor 1; MGC79402; pitrakinra

Search Names: IL4; IL-4; IL-4B_cell stimulatory factor 1;B cell growth factor 1; BCGF1; BCGF-1; interleukin 4; binetrakin; BCDF; B-cell stimulatory factor 1; BSF1; BSF-1; IL4E12; interleukin-4; Lymphocyte stimulatory factor 1; MGC79403; pitrakinra

Tag: IL-4