Human Recombinant CKMM | P1610

CK-MM is an isozyme of creatine kinase (CK). Cytosolic CK enzymes consist of two subunits, which can be either B (brain type) or M (muscle type). CK-MM is mainly expressed in skeletal muscle and can also be detected in heart muscle. It catalyses the conversion of creatine and consumes adenosine triphosphate (ATP) to create phosphocreatine and adenosine diphosphate (ADP). Creatine kinase is measured as a marker of myocardial infarction (heart attack), rhabdomyolysis (severe muscle breakdown), muscular dystrophy, etc.

P1610 | Human Recombinant CKMM DataSheet

Biomolecule/Target :

Synonyms: M-CK, Creatine kinase M chain, CKM; Creatine phosphokinase M-type; CPK-M

Alternates names: M-CK, Creatine kinase M chain, CKM; Creatine phosphokinase M-type; CPK-M

Taglines: An isozyme of creatine kinase expressed in skeletal muscle and heart

NCBI Gene ID #:

NCBI Gene Symbol:

Gene Source: Human

Accession #: AAH07462.1

Recombinant: TRUE

Source: E. coli

Purity by SDS-PAGE: ≥ 90% as determined by SDS-PAGE

Assay:

Purity:

Assay #2:

Endotoxin Level:

Activity (Specifications/test method):

Biological activity:

Results:

Binding Capacity:

Unit Definition:

Molecular Weight: The recombinant human CKMM consists of 396 amino acids and has a molecular mass of 44.9 KDa. It migrates as a ~45 KDa band in SDS-PAGE under reducing conditions.

Concentration:

Appearance: Liquid

Physical form description: Liquid

Reconstitution Instructions:

Amino acid sequence: A DNA sequence encoding the human CKM (AAH07462.1) (Met1-Lys381) was expressed with a polyhistidine tag at the N-terminus.

Handling: Centrifuge the vial prior to opening.

Usage: For Research Use Only! Not to be used in humans